Welcome to SNPeffect 4.0
Call: we are currently seeking beta-testers for the new SNPeffect 4.0 website. Your input and remarks are very important to us, so if you want to help us to improve the site and its tools, register for a beta-tester account now. After beta-testing, the site will open for everyone and registration will be removed (except for job submission).
SNPeffect is a database for phenotyping human single nucleotide polymorphisms (SNPs). SNPeffect primarily focuses on the molecular characterization and annotation of disease and polymorphism variants in the human proteome.
We provide a detailed variant analysis using our tools such as:
- TANGO to predict aggregation prone regions
- WALTZ to predict amylogenic regions
- LIMBO to predict hsp70 chaperone binding sites
- FoldX to analyse the effect on structure stability
Further, SNPeffect holds per-variant annotations on functional sites, structural features and post-translational modification.
Two new features are implemented in SNPeffect 4.0.
The meta-analysis tool enables scientists to carry out a large scale mining of SNPeffect data and visualize the results in a graph.
In SNPeffect 4.0 it is now possible to submit custom single protein variants for a detailed phenotypic analysis.
Credits
- SNPeffect 4.0 was developed by Greet De Baets and Joost Van Durme
- Previous versions of SNPeffect were developed by Joke Reumers
- The SNPeffect project was designed by Joost Schymkowitz and Frederic Rousseau
