SBNO1_HUMAN

Compact overview of SBNO1_HUMAN
UniProt Entry Name	SBNO1_HUMAN
Protein Name	Protein strawberry notch homolog 1
Protein Function	N.A
Length	1393 residues
Gene ontology overview of SBNO1_HUMAN
Cellular component	Molecular function	Biological process
ATP binding DNA binding hydrolase activity

Phenotypic summary of SBNO1_HUMAN

Short stretch summary of SBNO1_HUMAN
Predictor	Predicted regions overview	Stretches	Total score
Tango		21	4169
Waltz		17	3560
Limbo		26	10905
Domain composition of SBNO1_HUMAN
Database	Domain composition	Residue details
PFAM		ResIII (Residues 290-477)

TANGO aggregation profile of SBNO1_HUMAN

TANGO regions in SBNO1_HUMAN
N-term gatekeepers	TANGO region	C-term gatekeepers	Start	End	Score
EPGQD	LLLAAL	SESGI	8	13	8
QQPPS	TTTFVL	NQINH	85	90	24
VGKGR	TIAGIIY	ENYLL	330	336	48
SRKRA	LWFSVS	NDLKY	347	352	18
SVKKG	VIFATYSSLIG	ESQSG	396	406	72
KPTKT	GLAVL	ELQNK	456	460	7
NKAVK	LWVIA	RERFQ	564	568	61
KNGKC	VVIGL	QSTGE	627	631	19
DRKKL	YSLLGI	DLTAP	678	683	7
DGDKN	IAIIS	EAASS	935	939	21
VTAPE	YVFLIS	ELAGE	992	997	64
DVRQG	LIGVGLI	NVEDR	1079	1085	24
HQQNA	LFQYF	ADTLT	1121	1125	9
YFADT	LTAVV	QNAKK	1129	1133	13
SGHVE	LYTISV	ERGMS	1177	1182	12
GPDDG	FYLSLQI	RNNKK	1205	1211	13
RNNKK	TAILV	KEVNP	1217	1221	9
NPKKK	LFLVY	RPNTG	1230	1234	31
GLRCR	TYYVLCGSVLSVWTKVEGVL	ASVSG	1303	1322	37
EDGQR	IVGLI	IPANC	1345	1349	16
NCVSP	LVNLL	STSDQ	1358	1362	5

TANGO aggregation profile score plot
	This graph plots the per-residue TANGO aggregation score of the protein SBNO1_HUMAN. From left to right, all residue scores from the N-terminus to the C-terminus are plotted

WALTZ amylogenic profile of SBNO1_HUMAN

WALTZ regions in SBNO1_HUMAN
N-term gatekeepers	WALTZ region	C-term gatekeepers	Start	End	Score
PNGDR	AGFLIG	DGAGV	315	320	37
KGRTI	AGIIYENYL	LSRKR	332	340	19
LLSRK	RALWFS	VSNDL	345	350	16
NGSVK	KGVIFA	TYSSL	394	399	8
YNKAV	KLWVIA	RERFQ	563	568	22
KKSMW	GQFWSA	HQRFF	591	596	19
WSAHQ	RFFKYL	CIASK	599	604	20
TAKGV	LQSLIE	KHFPA	661	666	35
LPPNT	LDELID	ELGGP	874	879	10
LDVPV	EILNIT	EKQRF	918	923	15
MDGDK	NIAIIS	EAASS	934	939	66
VTAPE	YVFLIS	ELAGE	992	997	86
NKYGR	NALEIV	MKSIV	1044	1049	9
RQGLI	GVGLIN	VEDRS	1081	1086	25
HQQNA	LFQYFA	DTLTA	1121	1126	97
YSTSG	HVELYT	ISVER	1174	1179	17
TGKQL	KLEIYA	DLKKK	1243	1248	50

WALTZ aggregation profile score plot
	This graph plots the per-residue WALTZ amylogenic score of the protein SBNO1_HUMAN. From left to right, all residue scores from the N-terminus to the C-terminus are plotted

LIMBO chaperone binding profile of SBNO1_HUMAN

LIMBO regions in SBNO1_HUMAN
N-term gatekeepers	LIMBO region	C-term gatekeepers	Start	End	Score
VEPGQ	DLLLAALSE	SGISP	7	15	88.8
PLGST	IVMTKTPP	VTTNR	103	110	14.9
TNRQT	ITLTKFIQTTAS	TRPSV	118	129	42.8
QVQLK	DLLKNNSL	NELMK	156	163	22.6
SSNKE	GARMWIND	MKMRS	200	207	36.5
PPDVW	YKTSISEE	TIDNG	276	283	14.8
GIIYE	NYLLSRKR	ALWFS	338	345	100
GSVKK	GVIFATYS	SLIGE	395	402	36.3
GKYKT	RLKQLLHW	CGDDF	417	424	20.2
TGLAV	LELQNKLP	KARVV	460	467	52.6
MAYMN	RLGIWGEG	TPFRE	490	497	11.9
FKIEE	VLLSQSYVKMYNKA	VKLWV	548	561	32.3
NKAVK	LWVIARER	FQQAA	564	571	40.9
KVKRV	VQLARE	EIKNG	614	619	18.7
AKGVL	QSLIEKHFPAPDR	KKLYS	662	674	34.7
PDRKK	LYSLLGIDLTAPSNN	SSPRD	677	691	17.4
ENDPW	LIRKDHKK	NKEKK	778	785	96.3
QQMKK	DLLDKLEK	LAEDL	857	864	99.8
RVHMT	LELPWSAD	RAIQQ	965	972	100
YGRNA	LEIVMKSIVN	LDSPM	1046	1055	57.1
KSDVK	KFLTPGYS	TSGHV	1163	1170	96
NPKKK	LFLVYRPN	TGKQL	1230	1237	100
VLCGS	VLSVWTKV	EGVLA	1311	1318	6.3
NVKMQ	IVRLRTEDG	QRIVG	1334	1342	65.7
QRIVG	LIIPANCV	SPLVN	1348	1355	11.6
VSPLV	NLLSTSDQ	SQQLA	1360	1367	7.4

LIMBO chaperone binding profile score plot
	This graph plots the per-residue LIMBO chaperone binding score of the protein SBNO1_HUMAN. From left to right, all residue scores from the N-terminus to the C-terminus are plotted

All mutations from SBNO1_HUMAN

5 mutations listed

Variant	UniProt ID	Mutation	Disease	Mutation Type	dTANGO	dWALTZ	dLIMBO	ddG
VAR_057794	SBNO1_HUMAN	S729N	-	Polymorphism	0	0	0	N.A.
VAR_037913	SBNO1_HUMAN	S997C	A breast cancer sample	Unclassified	6	-87	0	N.A.
VAR_037912	SBNO1_HUMAN	E889K	A breast cancer sample	Unclassified	-2	0	0	N.A.
VAR_037911	SBNO1_HUMAN	S728N	-	Polymorphism	0	0	1	N.A.
VAR_037910	SBNO1_HUMAN	T634S	A breast cancer sample	Unclassified	-2	0	0	N.A.

Comma Separated Values document

Microsoft Excel document